韩德果,汉族,1979年9月生,河南南阳人。博士,教授,博(硕)士生导师。办公点:园艺楼309-3室 (0451-55191191),手机: 18946056863;E-mail: deguohan@neau.edu.cn
学习与工作经历
1999年9月 至2003年6月 河南师范大学生命科学学院 生物科学专业 理学学士;
2003年7月至2004年8月 河南省汝南县高级中学 生物教师;
2004年9月 至2007年6月 河南师范大学生命科学学院 植物学专业 理学硕士;
2007年9月 至2010年12月 中国农业大学 农学与生物技术学院 果树学专业 农学博士;
2010年12月 至2014年8月 东北农业大学园艺学院讲师、副教授,果树系教学主任;
2012年12月 至2016年7月 东北农业大学园艺学博士后流动站,博士后;
2014年9月 至2020年8月东北农业大学园艺园林学院副教授,硕士生导师,设施农业科学与工程系教学主任;
2019年1月 至2019年12月 借调国家自然科学基金委 生命科学部 农业环境与园艺科学处(原七处) 兼聘;
2020年9月 至今 东北农业大学园艺园林学院教授,博(硕)士生导师,设施农业科学与工程系党支部书记、教学主任。
社会兼职
国家自然科学基金、黑龙江省自然基金、湖南省自然基金等评审专家;中国园艺学会会员、中国园艺学会青年分会理事、中国园艺学会小浆果分会理事、黑龙江省园艺学会常务理事;黑龙江省三区人才精准扶贫专家、省级科技特派员。Plant Biotechnology Journal、Scientia Horticulturae、Frontiers in Plant Science、Functional & Integrative Genomics等杂志审稿人。
科研简述
主要研究方向为果树逆境生理与分子生物学、果树采后储运加工等。先后主持国家自然科学基金、黑龙江省自然科学基金、中国博士后科研基金等10余项,在国内外学术刊物上发表论文70余篇,其中第一或通讯作者SCI刊源文章近30篇。博士及工作后参与了国家863计划(2008AA10Z157)、国家自然科学基金(30800741、30971982);国家转基因专项(2009ZX08009-122B)、黑龙江省科技攻关(GC13B110)等10余项大中型课题的研究。
主持课题,先后主持国家自然基金、黑龙江省自然科学基金、中国博士后科研基金等10余项,具体如下:
1. 国家自然科学基金-面上项目(32172521)-- 苹果属山定子MbWRKY23介导MbCBF2调控植株抗寒的机制研究58.0万2022.1-2025.12;
2. 国家自然科学基金-青年项目(31301757)--小金海棠柠檬酸合成酶家族基因的克隆与功能分析22.0万2014.1-2016.12;
3. 中国博士后科学基金-一等资助(2013M530144)--小金海棠尼克烟酰胺合成酶家族基因的克隆与功能研究8.0万2013.5-2016.12;
4. 黑龙江省自然科学基金-联合引导项目(LH2019C031)--红树莓抗寒相关WRKY转录因子基因的确定与功能挖掘10.0万2019.7-2022.7;
5. 黑龙江省自然科学基金-面上项目(C2015015)--MxCS家族主效基因的确定及功能挖掘6.0万2015.7-2018.7;
6. 黑龙江博士后启动基金(LBH-Q16020)--小金海棠耐缺铁相关WRKY因子功能挖掘7.0万2016.12-2023.12;
7. 黑龙江省教育厅科研基金(12541004)--小金海棠柠檬酸合成酶家族主效基因的功能发掘3.0万2014.1-2016.12;
8. 黑龙江博士后科研基金(LBH2013ZZ133)--小金海棠尼克烟酰胺合成酶家族主效基因的确定与功能挖掘7.0万2013.10-2016.12;
9. 黑龙江省高校科技成果前期研发培育项目(1254CGZH17)--秋果型树莓高效栽培技术推广应用8.0万2014.1-2016.12;
10. 东北农业大学“学术骨干”计划项目(15XG06)--10.0万2015.7--2018.7;
11. 东北农业大学博士启动基金(2012RCB09)-- 6.0万2012.10-2015.12;
12. 农业部重点实验室开放课题(neauhc201803)-- 5.0万2018.6-2020.6;
13. 农业部重点实验室开放课题(neauhc201602)-- 3.0万2016.1-2017.12;
代表性论文,发表论文80余篇,其中一作及通讯SCI论文40余篇,如下(带❈为通讯作者,#为第一作者):
1. Deguo Han#, Yi Wang, Li Zhang, Li Ma, Xinzhong Zhang, Xuefeng Xu, Zhenhai Han❈. Isolation and functional characterization of MxCS1: a gene encoding a citrate synthase in Malus xiaojinensis. Biologia Plantarum (SCI, IF=1.747, JCR二区, 他引次数: 24次). 2012, 56:50–56.
2. Deguo Han#, Lei Wang, Yi Wang, Guohui Yang, Chao Gao, Zeyuan Yu, Tongyin Li, Xinzhong Zhang, Li Ma, Xuefeng Xu, Zhenhai Han❈. Overexpression of Malus xiaojinensis CS1 gene in tobacco affects plant development and increases iron stress tolerance. Scientia Horticulturae (SCI, 中科院二区TOP,JCR一区,IF=3.463, 他引次数: 20次). 2013, 150:65–72.
3. Deguo Han#❈, Guohui Yang, Kedong Xu, Qin Shao, Zeyuan Yu, Bing Wang, Qiulai Ge, Yang Yu. Overexpression of a Malus xiaojinensis Nas1 gene influences flower development and tolerance to iron stress in transgenic tobacco. Plant Molecular Biology Reporter (SCI, IF=2.304, JCR二区, 他引次数: 18次). 2013, 31:802–809.
4. Deguo Han#❈, Yan Shi, Zeyuan Yu, Wei Liu, Bingyu Lv, Bing Wang, Guohui Yang❈. Isolation and functional analysis of MdCS1: a gene encoding a citrate synthase in Malus domestica (L.) Borkh. Plant Growth Regulation (SCI, IF=3.412, JCR二区, 他引次数: 16次). 2015, 75:209–218.
5. Deguo Han#❈, Yan Shi, Bing Wang, Wei Liu, Zeyuan Yu, Bingyu Lv, Guohui Yang❈. Isolation and preliminary functional analysis of MxCS2: a gene encoding a citrate synthase in Malus xiaojinensis. Plant Molecular Biology Reporter (SCI, IF=2.304, JCR二区, 他引次数: 21次). 2015, 33:133–142.
6. Guohui Yang#, Jin Li#, Wei Liu, Zeyuan Yu, Yan Shi, Bingyu Lv, Bing Wang, Deguo Han❈. Molecular cloning and characterization of MxNAS2, a gene encoding nicotianamine synthase in Malus xiaojinensis, with functions in tolerance to iron stress and misshapen flower in transgenic tobacco. Scientia Horticulturae (SCI, 中科院二区TOP, JCR一区, IF=3.463, 他引次数: 36次). 2015, 183:77–86. IF=2.769
7. Deguo Han#❈, Yufang Wang, Zhaoyuan Zhang, Qianqian Pu, Haibin Ding, Jiaxin Han, Tingting Fan, Xue Bai, Guohui Yang❈. Isolation and functional analysis of MxCS3: a gene encoding a citrate synthase in Malus xiaojinensis, with functions in tolerance to iron stress and abnormal flower in transgenic Arabidopsis thaliana. Plant Growth Regulation (SCI, IF=3.412, JCR二区, 他引次数: 20次). 2017, 82:479–489.
8. Deguo Han#❈, Zhaoyuan Zhang, Haibin Ding, Lijing Chai, Wei Liu, Hongxia Li, Guohui Yang❈. Isolation and characterization of MbWRKY2 gene involved in enhanced drought tolerance in transgenic tobacco. Journal of Plant Interactions (SCI, IF=4.208, JCR一区, 他引次数: 26次). 2018, 13:163–172.
9. Deguo Han#❈, Yanjie Hou, Wei Liu, Zhaoyuan Zhang, Haibin Ding, Hongxia Li, Guohui Yang❈. Isolation and functional analysis of MdNAS1, with functions in improved iron stress tolerance and abnormal flower in transgenic tobacco. Journal of Plant Interactions (SCI, IF=4.208, JCR一区, 他引次数: 4次). 2018, 13:213–220.
10. Deguo Han#❈, Zhaoyuan Zhang, Haibin Ding, Yufang Wang, Wei Liu, Hongxia Li, Guohui Yang❈. Molecular cloning and functional analysis of MbWRKY3 involved in improved drought tolerance in transformed tobacco. Journal of Plant Interactions (SCI, IF=4.208, JCR一区, 他引次数: 17次). 2018, 13:329–337.
11. Deguo Han#, Zhaoyuan Zhang, Boxin Ni, Haibin Ding, Wei Liu, Wenhui Li❈, Lijing Chai, Guohui Yang❈. Isolation and functional analysis of MxNAS3 involved in enhanced iron stress tolerance and abnormal flower in transgenic Arabidopsis. Journal of Plant Interactions (SCI, IF=4.208, JCR一区, 他引次数: 12次). 2018, 13:433–441.
12. Deguo Han#❈, Yanjie Hou, Haibin Ding, Zhengyi Zhou, Hongxia Li, Guohui Yang❈. Isolation and preliminary functional analysis of MbWRKY4 gene involved in salt tolerance in transgenic tobacco. International Journal of Agriculture & Biology (SCI, IF=0.869, 他引次数: 10次). 2018, 20:2045–2052.
13. Deguo Han#, Haibin Ding, Lijing Chai, Wei Liu, Zhaoyuan Zhang, Yanjie Hou, Yang Guohui❈. Isolation and characterization of MbWRKY1, a WRKY transcription factor gene from Malus baccata (L.) Borkh involved in drought tolerance. Canadian Journal of Plant Science (SCI, IF=1.018, 他引次数: 20次). 2018, 98:1023–1034.
14. Deguo Han#, Yanjie Hou, Yufang Wang, Boxin Ni, Zitong Li, Guohui Yang❈. Overexpression of a Malus baccata WRKY transcription factor gene (MbWRKY5) increases drought and salt tolerance in transgenic tobacco. Canadian Journal of Plant Science (SCI, IF=1.018, 他引次数: 22次). 2019, 99:173–183.
15. Guohui Yang, Ruining Hou, Wei Zhang, Juanjuan Qu, Hongxia Li, Hongzhe Dou, Guo Cheng, Deguo Han❈. Bacterial and fungal diversity in rhizosphere soil of red raspberry (Rubus idaeus L. cv. Heritage). Allelopathy Journal (SCI, IF=1.275). 2019,47 (1):127–136.
16. Guohui Yang#, Hongxia Li#, Yueyan Xin, Heng Yu, Letian Chen, Ling Li, Deguo Han❈. Effect of abscisic acid on expression of its key enzyme synthesis genes, RiNCED1 and RiCYP707A1, and quality of raspberry (Rubus idaeus) fruits. International Journal of Agriculture & Biology (SCI, IF=0.869, 他引次数: 1次). 2020, 23:269–278.
17. Ning Hao#, Deguo Han#, Ke Huang, Yalin Du, Jingjing Yang, Jian Zhang, Changlong Wen❈, Tao Wu❈. Genome‑based breeding approaches in major vegetable crops. Theoretical and Applied Genetics (SCI, 中科院一区TOP, JCR一区, IF=5.699; 他引次数: 21次). 2020, 133:1739–1752.
18. Hui Yuan, Pengtao Yue, Haidong Bu, Deguo Han❈, Aide Wang❈. Genome-wide analysis of ACO and ACS genes in pear (Pyrus ussuriensis). In Vitro Cellular & Developmental Biology - Plant (SCI, IF=2.252, JCR二区, 他引次数: 11次). 2020, 56:193–199.
19. Zhihua Cheng, Shibin Zhuo, Xiaofeng Liu, Gen Che, Zhongyi Wang, Ran Gu, Junjun Shen, Weiyuan Song, Zhaoyang Zhou, Deguo Han❈, Xiaolan Zhang❈. The MADS-box gene CsSHP participates in fruit maturation and floral organ development in cucumber. Frontiers in Plant Science (SCI, 中科院二区, JCR一区, IF=5.753; 他引次数: 7次). 2020, 10:1781.
20. Deguo Han#, Man Du, Zhengyi Zhou, Shuang Wang, Tiemei Li❈, Jiaxin Han, Tianlong Xu, Guohui Yang❈. Overexpression of a Malus baccata NAC transcription factor gene MbNAC25 increases cold and salinity tolerance in Arabidopsis. International Journal of Molecular Sciences (SCI, 中科院二区TOP, JCR一区, IF=5.923; 他引次数: 38次). 2020, 21:1198;
21. Xisen Yuan, Zipeng Yu, Lin Liu, Yang Xu, Lei Zhang, Deguo Han❈, Shizhong Zhang❈. Genome-wide identification and expression analysis of asparagine synthetase family in apple. Journal of Integrative Agriculture (SCI, 中科院二区, JCR一区, IF=2.848). 2020, 19(5):1261–1273.
22. Deguo Han#, Jiaxin Han, Guohui Yang, Shuang Wang, Tianlong Xu, Wenhui Li❈. An ERF Transcription Factor Gene fromMalus baccata(L.) Borkh,MbERF11, Affects Cold and Salt Stress Tolerance inArabidopsis. Forests (SCI, 中科院二区, JCR一区, IF=2.633; 他引次数: 30次). 2020, 11:514.
23. Deguo Han#, Man Du, Zhengyi Zhou, Shuang Wang, Tiemei Li❈, Jiaxin Han, Tianlong Xu, Guohui Yang❈. An NAC transcription factor gene fromMalus baccata,MbNAC29, increases cold and high salinity tolerance inArabidopsis. In Vitro Cellular & Developmental Biology - Plant (SCI, IF=2.252, JCR二区, 他引次数:20次). 2020,56:588–599.
24. Deguo Han#, Zhengyi Zhou, Man Du, Tiemei Li❈, Xuemei Wu, Jing Yu, Peng Zhang, Guohui Yang❈. Overexpression of aMalus xiaojinensisWRKYtranscription factor gene (MxWRKY55) increased iron and high salinity stress tolerance inArabidopsis thaliana. In Vitro Cellular & Developmental Biology - Plant (SCI, IF=2.252, JCR二区, 他引次数: 10次). 2020, 56:600–609.
25. Deguo Han#, Jiaxin Han, Tianlong Xu, Tiemei Li❈, Chunya Yao, Yijia Wang, Dejia Luo, Guohui Yang❈. Isolation and preliminary functional characterization of MxWRKY64, a new WRKY transcription factor gene from Malus xiaojinensis Cheng et Jiang. In Vitro Cellular & Developmental Biology - Plant (SCI, IF=2.252, JCR二区, 他引次数: 10次). 2021,57:202–213.
26. Deguo Han#, Jiaxin Han, Tianlong Xu, Xingguo Li❈, Chunya Yao, Tiemei Li, Xiaohan Sun, Xinhui Wang, GuohuiYang❈. Overexpression of MbERF12, an ERF gene from Malus baccata (L.) Borkh increases cold and salt tolerance in Arabidopsis thaliana associated with the ROS scavenging through ethylene signal transduction. In Vitro Cellular & Developmental Biology - Plant (SCI, IF=2.347, JCR二区, 他引次数: 8次). 2021, 57: 760–770.
27. Guohui Yang, Yuxiao Chen, Heng Yu, Hang Zhang, Deguo Han❈, Xiaoyu Guo, Enqing Yan, Hanyi Quan, Tiemei Li❈. Raspberry (Rubus idaeus L.) NCED1 gene enhances high salinity and cold tolerance in Arabidopsis. In Vitro Cellular & Developmental Biology - Plant (SCI, IF=2.347, JCR二区, 他引次数: 1次). 2021, 57: 811–819.
28. Chunya Yao, Xingguo Li, Yingmei Li, Guohui Yang, Wanda Liu, Bangtao Shao, Jiliang Zhong, Pengfei Huang, Deguo Han❈. Overexpression of a Malus baccata MYB transcription factor gene MbMYB4 increases cold and drought tolerance in Arabidopsis thaliana. International Journal of Molecular Sciences (SCI, 中科院二区TOP, JCR一区, IF=6.208; 他引次数:13次). 2022, 23, 1794.
29. Chunya Yao, Wenhui Li, Xiaoqi Liang, Chuankun Ren, Wanda Liu, Guohui Yang, Mengfei Zhao, Tianyu Yang, Xingguo Li❈, Deguo Han❈. Molecular cloning and characterization of MbMYB108, a Malus baccata MYB transcription factor gene, with functions in tolerance to cold and drought stress in transgenic Arabidopsis thaliana. International Journal of Molecular Sciences (SCI, 中科院二区TOP, JCR一区, IF=6.208; 他引次数:11次). 2022, 23, 4846.
30. Deguo Han, Tianlong Xu, Jiaxin Han, Wanda Liu, Yu Wang, Xingguo Li❈, Xiaohan Sun, Xinhui Wang, Tiemei Li, Guohui Yang❈. Overexpression of MxWRKY53 increased iron and high salinity stress tolerance in Arabidopsis thaliana. In Vitro Cellular & Developmental Biology - Plant (SCI, IF=2.347, JCR二区, 他引次数:6次). 2022, 58: 266–278.
31. Xiaoqi Liang, Yingmei Li, Anqi Yao, Wanda Liu, Tianyu Yang, Mengfei Zhao, Bingxiu Zhang❈, Deguo Han❈. Overexpression of MxbHLH18 increased iron and high salinity stress tolerance in Arabidopsis thaliana. International Journal of Molecular Sciences (SCI, 中科院二区TOP, JCR一区, IF=6.208; 他引次数:11次). 2022, 23, 8007.
32. Yingmei Li, Jiliang Zhong, Pengfei Huang, Bangtao Shao, Wenhui Li❈, Wanda Liu, Yu Wang, Liping Xie, Meina Han, Deguo Han❈. Overexpression of MxFRO6, a FRO gene from Malus xiaojinensis, increases iron and salt tolerance in Arabidopsis thaliana. In Vitro Cellular & Developmental Biology - Plant (SCI, JCR二区, IF=2.347; 他引次数:2次). 2022, 58: 189–199.
33. Xingguo Li, Xiaoqi Liang, Wenhui Li, Anqi Yao, Wanda Liu, Yu Wang, Guohui Yang❈, Deguo Han❈. Isolation and functional analysis of MbCBF2, a Malus baccata (L.) Borkh CBF transcription factor gene, with functions in tolerance to cold and salt stress in transgenic Arabidopsis thaliana. International Journal of Molecular Sciences (SCI, 中科院二区TOP, JCR一区, IF=6.208; 他引次数:5次). 2022, 23, 9827.
34. Lijie Han, Xiaofei Song, Zhongyi Wang, Xiaofeng Liu, Liying Yan, Deguo Han❈, Zhaoyang Zhou❈, Xiaolan Zhang. Genome-wide analysis of OVATE family proteins in cucumber (Cucumis sativus L.). Journal of Integrative Agriculture (SCI, 中科院一区TOP, IF=4.384;他引次数:3次). 2022, 21(5): 1321–1331.
35. Wenhui Li, Jiliang Zhong, Lihua Zhang, Yu Wang, Penghui Song, Wanda Liu, Xingguo Li❈, Deguo Han❈. Overexpression of a Fragaria vesca MYB transcription factor gene (FvMYB82) increases salt and cold tolerance in Arabidopsis thaliana. International Journal of Molecular Sciences (SCI, 中科院二区TOP, JCR一区, IF=6.208; 他引次数:4次). 2022, 23, 10538.
36. Xiaoqi Liang, Guijie Luo, Wenhui Li, Anqi Yao, Wanda Liu, Liping Xie, Meina Han, Xingguo Li❈, Deguo Han❈. Overexpression of a Malus baccata CBF transcription factor gene, MbCBF1, increases cold and salinity tolerance in Arabidopsis thaliana. Plant Physiology and Biochemistry. (SCI, 中科院二区, JCR一区, IF=5.437; 他引次数:3次). 2022, 192: 230–242.
37. Wei Liu, Xiaoqi Liang, Weijia Cai, Hao Wang, Xu Liu, Longfei Cheng, Penghui Song, Guijie Luo❈, Deguo Han❈. Isolation and functional analysis of VvWRKY28, a Vitis vinifera WRKY transcription factor gene, with functions in tolerance to cold and salt stress in transgenic Arabidopsis thaliana. International Journal of Molecular Sciences (SCI, 中科院二区TOP, JCR一区, IF=6.208; 他引次数:1次). 2022, 23, 13418.
38. Yadong Duan, Jiaxin Han, Baitao Guo, Wenbo Zhao, Shuang Zhou, Chunwei Zhou, Lei Zhang, Xingguo Li, Deguo Han*. MbICE1 confers drought and cold tolerance through up-regulating antioxidant capacity and stress-resistant genes in Arabidopsis thaliana. International Journal of Molecular Sciences (SCI, 中科院二区TOP, JCR一区, IF=6.208; 他引次数:0次). 2022, 23, 16072.
39. Jiaxin Han, Xingguo Li, Wenhui Li, Qian Yang, Zhenghao Li, Zhi Cheng, Long Lv, Lihua Zhang❈, Deguo Han❈. Isolation and preliminary functional analysis of FvICE1, involved in cold and drought tolerance in Fragaria vesca through overexpression and CRISPR/Cas9 technologies . Plant Physiology and Biochemistry. (SCI, 中科院二区, JCR一区, IF=5.437, 他引次数:1次). 2023, 196:270–280.
40. Wanda Liu, Tianhe Wang, Yu Wang, Xiaoqi Liang, Jilong Han, Deguo Han❈. MbMYBC1 confers drought and cold tolerance through up-regulating stress-resistant genes and antioxidant capacity in transgenic Arabidopsis. Frontiers in Plant Science (SCI, 中科院二区, JCR一区, IF=6.627). 2023, 14:1141446.
教学工作
本科生课程:主讲设施果树栽培、遗传学等理论课;设施果树栽培实验、遗传学实验、果树综合大实验等实验课;果品文化、中国茶文化鉴赏等通识选修课。
研究生课程:主讲果树分子生物学(204206)、果树次生代谢(204309)、植物逆境响应与调控(304324)。
出版教材
《植物组织培养》(第二版, ISBN: 9787122163448) 参编. 普通高等教育“十二五”规划教材. 化学工业出版社,2013年.
《龙江果树》(ISBN:9787567407237)参编. 东北林业大学出版社,2016年.
获奖、品种、专利 等
1. 2014年,审定树莓新品种“秋福”,黑龙江省农作物品种登记(黑登记2014038),第3完成人;
2. 2014年,中共东北农业大学“科研先锋岗”获得者;
3. 2014年,“哈尔滨市自然科学技术学术成果奖”(2013416)获得者;
4. 韩振海,韩德果,王忆,张新忠。小金海棠MxCS基因及编码蛋白与应用,国家发明专利授权号:ZL 201010165100.1;
5. 2015年,东农学者首批 “学术骨干” 计划项目获得者;
6. 2018年,东北农业大学 “优秀共产党员” 称号获得者;
7. 2021年,东北农业大学 园艺园林学院 “优秀共产党员” 称号获得者。
培养学生情况
1. 近年来,指导本科生30余人(已毕业19人),年均指导本科生主持SIPT项目1项。
2. 指导的硕士研究生23人(已毕业10人)。指导的研究生连续多年获得国家奖学金:王玉芳(2017)、张兆源(2018)、侯妍杰(2019)、杜漫(2020)、韩家鑫(2021)、姚春雅(2022)、李迎梅(2022);1人获得“黑龙江省三好学生”称号:张兆源(2019)。材料截止2023年3月1日